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Daytime Nighttime Cold Flu Relief (CVS Pharmacy)

Available Formats

Dosage Form Package Information Links
KIT 1 KIT in 1 CARTON (59779-491-48) * 8 CAPSULE in 1 BLISTER PACK * 8 CAPSULE in 1 BLISTER PACK Label Information

Complete Daytime Nighttime Cold Flu Relief Information

  • Active ingredients for Daytime (in each softgel)

    Acetaminophen 325 mg

    Dextromethorphan HBr 10 mg

    Phenylephrine HCl 5 mg


  • Active ingredients for Nighttime (in each softgel)

    Acetaminophen 325 mg

    Dextromethorphan HBr 15 mg

    Doxylamine succinate 6.25 mg


  • Purpose for Daytime

    Pain reliever/fever reducer

    Cough suppressant

    Nasal decongestant


  • Purpose for Nighttime

    Pain reliever/fever reducer

    Cough suppressant

    Antihistamine


  • Uses

    • temporarily relieves common cold and flu symptoms:
      • sore throat
      • headache
      • minor aches and pains
      • fever
      • cough due to minor throat and bronchial irritation
      • nasal congestion (Daytime only)
      • runny nose and sneezing (Nighttime only)

  • Warnings

    Liver warning: These products contain acetaminophen. Severe liver damage may occur if you take:

    • more than 4,000 mg of acetaminophen in 24 hours
    • with other drugs containing acetaminophen
    • 3 or more alcoholic drinks every day while using these products

    Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

    Do not use
    • to make a child sleep (Nighttime only)
    • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
    • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

    Ask a doctor before use if you have
    • liver disease
    • cough that occurs with too much phlegm (mucus)
    • trouble urinating due to an enlarged prostate gland
    • persistent or chronic cough such as occurs with smoking, asthma, emphysema, and (for Nighttime only) chronic bronchitis
    • glaucoma (Nighttime only)
    • diabetes (Daytime only)
    • heart disease (Daytime only)
    • thyroid disease (Daytime only)
    • high blood pressure (Daytime only)

    Ask a doctor or pharmacist before use if you are
    • taking the blood thinning drug warfarin
    • taking sedatives or tranquilizers (Nighttime only)

    When using this product,

    do not exceed recommended dosage.

    In addition, when using Nighttime:

    • excitability may occur, especially in children
    • avoid alcoholic drinks
    • marked drowsiness may occur
    • alcohol, sedatives, and tranquilizers may increase drowsiness
    • be careful when driving a motor vehicle or operating machinery

    Stop use and ask a doctor if
    • nervousness, dizziness or sleeplessness occur (Daytime only)
    • pain, cough, and (for Daytime only) nasal congestion gets worse or lasts more than 7 days
    • fever gets worse or lasts more than 3 days
    • redness or swelling is present
    • new symptoms occur
    • cough comes back or occurs with rash or headache that lasts

    These could be signs of a serious condition.

    If pregnant or breast-feeding,

    ask a health professional before use.

    Keep out of reach of children.

    Overdose warning: Taking more than the recommended dose can cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • Directions

    • do not take more than directed (see Overdose warning)
    • do not take more than 4 doses in 24 hours
    • swallow whole; do not crush, chew, or dissolve

    Daytime: adults and children 12 years and over: take 2 softgels with water every 4 hours.

    Nighttime: adults and children 12 years and over: take 2 softgels with water very 6 hours.

    • children under 12 years: do not use

  • Other information

    • store at room temperature 15°-30°C (59°-86°F)
    • avoid excessive heat

  • Inactive ingredients

    in Daytime butylated hydroxyanisole, butylated hydroxytoluene, edible white ink, FD&C red #40*, FD&C yellow #6, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, sorbitan, sorbitol      *may contain this ingredient

    in Nighttime D&C yellow #10, edible white ink, FD&C blue #1, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, purified water, sorbitan, sorbitol


  • Questions or comments?

    Call 1-877-753-3935 Monday-Friday 9AM-5PM EST


  • Principal Display Panel

    Compare to Vicks® NyQuil® and Vicks® DayQuil® LiquiCaps® active ingredients†

    Non-Drowsy DAYTIME COLD & FLU RELIEF

    Multi-Symptom

    • Fever, aches & sore throat
    • Cough
    • Nasal congestion

    ACETAMINOPHEN, Dextromethorphan HBr, Phenylephrine HCl

    Alcohol free, Antihistamine free

    DAYTIME SOFTGELS

    Multi-Symptom NIGHTTIME COLD & FLU RELIEF

    • Fever, aches & sore throat
    • Cough
    • Runny nose

    ACETAMINOPHEN, Dextromethorphan HBr, Doxylamine Succinate

    Alcohol free

    NIGHTTIME SOFTGELS

    †This product is not manufactured or distributed by Procter & Gamble, owner of the registered trademarks Vicks®, DayQuil®, NyQuil® and LiquiCaps®.

    Distributed by: CVS Pharmacy, Inc.

    One CVS Drive, Woonsocket, RI  02895

    www.cvs.com   1-800-shop-CVS

    TAMPER EVIDENT: DO NOT USE IF CARTON IS OPENED OR IF BLISTER UNIT IS TORN, BROKEN OR SHOWS ANY SIGNS OF TAMPERING.

    KEEP OUTER CARTON FOR COMPLETE WARNINGS AND PRODUCT INFORMATION.


  • Product Label

    Acetaminophen 325 mg, Dextromethorphan HBr 10 mg, Phenylephrine HCl 5 mg, Dextromethorphan HBr 15 mg, Doxylamine succinate 6.25 mg

    CVS Daytime and Nighttime Cold Flu Relief Softgels


  • INGREDIENTS AND APPEARANCE
    DAYTIME NIGHTTIME COLD FLU RELIEF 
    acetaminophen, dextromethorphan hbr, doxylamine succinate, phenylephrine hcl kit
    Product Information
    Product Type HUMAN OTC DRUG Item Code (Source) NDC:59779-491
    Packaging
    # Item Code Package Description Marketing Start Date Marketing End Date
    1 NDC:59779-491-48 1 in 1 CARTON
    Quantity of Parts
    Part # Package Quantity Total Product Quantity
    Part 1 2 BLISTER PACK 16 
    Part 2 4 BLISTER PACK 32 
    Part 1 of 2
    NIGHTTIME COLD FLU RELIEF 
    acetaminophen, dextromethorphan hydrobromide, doxylamine succinate capsule
    Product Information
    Route of Administration ORAL
    Active Ingredient/Active Moiety
    Ingredient Name Basis of Strength Strength
    ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D) ACETAMINOPHEN 325 mg
    DEXTROMETHORPHAN HYDROBROMIDE (UNII: 9D2RTI9KYH) (DEXTROMETHORPHAN - UNII:7355X3ROTS) DEXTROMETHORPHAN HYDROBROMIDE 10 mg
    DOXYLAMINE SUCCINATE (UNII: V9BI9B5YI2) (DOXYLAMINE - UNII:95QB77JKPL) DOXYLAMINE SUCCINATE 6.25 mg
    Inactive Ingredients
    Ingredient Name Strength
    D&C YELLOW NO. 10 (UNII: 35SW5USQ3G)  
    FD&C BLUE NO. 1 (UNII: H3R47K3TBD)  
    GELATIN (UNII: 2G86QN327L)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    POLYETHYLENE GLYCOLS (UNII: 3WJQ0SDW1A)  
    POVIDONES (UNII: FZ989GH94E)  
    PROPYLENE GLYCOL (UNII: 6DC9Q167V3)  
    WATER (UNII: 059QF0KO0R)  
    SORBITAN (UNII: 6O92ICV9RU)  
    SORBITOL (UNII: 506T60A25R)  
    Product Characteristics
    Color GREEN Score no score
    Shape CAPSULE Size 21mm
    Flavor Imprint Code P30;94A;35A
    Contains     
    Packaging
    # Item Code Package Description Marketing Start Date Marketing End Date
    1 8 in 1 BLISTER PACK
    Marketing Information
    Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
    OTC MONOGRAPH FINAL part341
    Part 2 of 2
    DAYTIME COLD FLU RELIEF 
    acetaminophen, dextromethorphan hbr, phenylephrine hcl capsule
    Product Information
    Route of Administration ORAL
    Active Ingredient/Active Moiety
    Ingredient Name Basis of Strength Strength
    ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D) ACETAMINOPHEN 325 mg
    DEXTROMETHORPHAN HYDROBROMIDE (UNII: 9D2RTI9KYH) (DEXTROMETHORPHAN - UNII:7355X3ROTS) DEXTROMETHORPHAN HYDROBROMIDE 15 mg
    PHENYLEPHRINE HYDROCHLORIDE (UNII: 04JA59TNSJ) (PHENYLEPHRINE - UNII:1WS297W6MV) PHENYLEPHRINE HYDROCHLORIDE 5 mg
    Inactive Ingredients
    Ingredient Name Strength
    BUTYLATED HYDROXYANISOLE (UNII: REK4960K2U)  
    BUTYLATED HYDROXYTOLUENE (UNII: 1P9D0Z171K)  
    FD&C RED NO. 40 (UNII: WZB9127XOA)  
    FD&C YELLOW NO. 6 (UNII: H77VEI93A8)  
    GELATIN (UNII: 2G86QN327L)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    POLYETHYLENE GLYCOLS (UNII: 3WJQ0SDW1A)  
    POVIDONES (UNII: FZ989GH94E)  
    PROPYLENE GLYCOL (UNII: 6DC9Q167V3)  
    WATER (UNII: 059QF0KO0R)  
    SORBITAN (UNII: 6O92ICV9RU)  
    SORBITOL (UNII: 506T60A25R)  
    Product Characteristics
    Color ORANGE Score no score
    Shape CAPSULE Size 21mm
    Flavor Imprint Code P19;95A;36A
    Contains     
    Packaging
    # Item Code Package Description Marketing Start Date Marketing End Date
    1 8 in 1 BLISTER PACK
    Marketing Information
    Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
    OTC MONOGRAPH FINAL part341 05/31/2013
    Marketing Information
    Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
    OTC MONOGRAPH FINAL part341 05/31/2013
    Labeler - CVS Pharmacy (062312574)
    Registrant - P and L Development of New York Corporation (800014821)